Medical science is a detective that tries to understand what goes on the human body. Medicine still has a very limited knowledge of what goes inside us as we are immensely complex. The human body is extremely complex and our knowledge of it barely scratch the surface of this elaborated composition.
At Newbery Medicine we understand the practice of medicine as a way to help people facilitate the amazingly complex capacity of the human body for repairing its own self. We do not envision our treatment as “curative”. Cure is a state that only the body by itself can achieve. So our actions and advise acts as an enhancement to the natural mechanisms the body possess.
Newbery Medicine is dedicated to understand and treat inflammatory conditions. Inflammation is a new approach to a more classical view of the “autoimmune diseases”. It involves a great amount of ailments that share in common multiple medical conditions.
Many of these “inflammatory diseases” have shown a common pattern: they have unbalanced gut microorganisms, even diseases like psoriasis, multiple sclerosis or rheumatoid arthritis that would make us think their origin is far away from the gut, share similar patterns of abnormal microbial populations.
The treatments available to treat the ever increasing number of inflamed patients tend to grow in aggressiveness and invasion over the already frail bodies. The therapeutic techniques generally used have very poor results and expose the patient to enormous risks without the corresponding efficiency. This equation of low efficiency at high risk is very discouraging for many. Furthermore, the costs of these new therapeutic techniques are soaring, inflicting an extra burden to patients who have to pay for them. In this sense we received a couple that has a girl with Crohn´s disease that did not want to expose her to the drugs offered by their gastroenterologist. We did apply her FMTs and she could control the inflammation (normalize her Fecal Calprotectin) and form stools for the first time in her life among many other improvements. The side effects of this therapy were none.
In this direction, the good results we obtained with novel approaches lead to the creation of Newbery Medical and its team of specialists, a center dedicated exclusively to treat inflammatory diseases. The results we are seeing are very encouraging.
Most treatments applied in chronic diseases should in general be maintained throughout the life of the sufferer. For example, diabetic insulin must be used for the entire life of the patient, just the same seems to be with anti-inflammatory therapies that should be kept in use for a long time in the very few cases where they are effective.
The therapeutic approach for Ulcerative Colitis used by mainstream medicine today resides on two approaches: one is the modification of the immunologic response via “biologic drugs” and the other is to “cure” the body by surgically amputation of the large intestine (colectomy) where the disease is supposed to reside. But with great surprise most of the patients that opt for the surgical “solution”, end up with the same predicament but in worst condition as they lost the colon in the way to fix their problem. We see it repeatedly, once the colon is removed, patients show some relief for a short period, after which the symptoms return and new problems appear.
Now it is clearly known that the disease resides throughout the body, inflammation of the bowel may be just the organ where this process is expressed, but many patients show not only gut problems, the liver, eyes, joints, skin, blood, and the list goes on, are associated with the intestinal problems. These extra intestinal symptoms do not improve after the gut removal.
The quality of life of a patient suffering from ulcerative colitis or Crohn’s disease is very poor, they live in terror for not being able to reach the bathroom in time, diapers, pains before, during and after a bowel movement. Crohn´s patients usually need to receive surgical procedures to relieve obstructions of fistulas, they will gradually lose parts of their guts. They usually bleed have anemia and may need blood replacement, also in the youngest thriving is a common problem. They can´t keep weight, are malnourished, and suffer many other dangerous health situations.
The therapeutic approach to help them should avoid adding new problems to the already existing. The available drugs so far are ineffective and involve a high risk. They have very low efficacy as good responses are achieved only in about 41-42% of all cases with the best therapeutic approach to control of inflammation and symptoms, the rest, about 60% of all treated patients, do not show any positive response to medications. But this would be tolerable if despite having low effectiveness they would entail low risk. Most of the drugs used to treat inflammation have very high risks.
Any medical intervention on the body involves some degree of risk. From surgery to medicate with a “innocent” vitamin, it involves intervening in a complex system where every action entails a huge number of possible complex reactions. The more aggressive the greater risk of any action. Overall risk is conceived as a necessary evil to cure major diseases, but when time comes to try to cure a minor illness as it could the case with inflammation and the possible outcome of that side effect is cancer, then the application of that method or drug has no justification.
The great contribution of recent years has been the discovery of the existence of a huge number of microscopic inhabitants over and in our bodies that are denominated microbiota. One of the most crucial ones is the intestinal bacterial population that weights about one kilo and mainly resides in our colon.
The transplant of bacteria from a healthy donor into a sick patient has been showed to be a very successful approach to change the course of one disease Clostridium difficile infection. Many other diseases, including inflammatory bowel, are showing extremely good results to the initial treatments. A great deal of research is still under way, the most striking feature of this therapy beyond the surprising good outcomes, is that it is safe, only minor problems have been reported as negative outcomes, never an important infection nor any death as a result of its usage.
Therefore, in Newbery Medicine we are dedicated to research and treat people using this novel technique on patients with intestinal inflammation and other inflammatory diseases which list continues to grow as well as the sophistication of the procedures and preparation of the recipients. At the same time, we may treat with great success a great deal of other diseases that may get the benefit of replacing the altered intestinal flora with a new one originated in a healthy donor.